Care journey

What the first 90 days of metabolic care look like.

GLP-1 therapy is not a quick fix. Here is an honest, timeline-based view of what to expect from assessment through your first renewal.

Phase 1 — Days 0–7

Assessment & provider review.

Day 0

Assessment submitted

Complete your 8-question eligibility intake. No credit card is required. Your answers are encrypted and transmitted securely to our clinical review team.

Days 1–2

Provider review begins

A licensed physician or nurse practitioner reviews your full health history, checks contraindications, and evaluates clinical eligibility for GLP-1 therapy.

Day 1–3

Eligibility decision + onboarding

You receive a decision via email. If approved, you complete membership enrollment and the onboarding fee is charged. If not approved, no charge applies.

Days 3–7

Prescription sent to pharmacy

Your provider sends a prescription to an NABP-verified pharmacy. Most first shipments arrive within 5–7 days of prescription issuance.

Phase 2 — Weeks 2–4

First dose & early response.

The first few weeks are the adjustment period. Most people experience some GI side effects (nausea, mild discomfort) as their body adapts to the medication. These typically resolve within 2–4 weeks and are managed by starting at the lowest effective dose.

What to expect weeks 1–4

Appetite changes

Most members notice reduced appetite within the first 1–2 weeks. This is the primary mechanism of GLP-1 therapy.

GI side effects

Nausea and mild discomfort are common early on. Starting on the lowest dose minimizes this significantly.

Day 14 check-in

Your care coordinator reviews your response and addresses any side effect concerns before dose adjustment decisions.

No early results

Most metabolic changes take 4–12 weeks to become measurable. Week 2 is too early to assess outcomes.

Day 14

First care coordinator check-in

Review your early response, discuss any side effects, and confirm next steps. Dose adjustment decisions are made at or after this point based on your response.

Phase 3 — Weeks 4–8

Titration & response tracking.

As your body adjusts to the starting dose, your provider may recommend a dose increase (titration) based on your response and tolerability. This phase is where most members begin to see measurable changes in weight and metabolic markers.

Day 30

Month 1 review + renewal

Your provider reviews your 30-day data. If progressing well, your membership renews automatically. You can cancel at any point before the renewal date.

Weeks 4–8

Dose titration (if applicable)

Based on your response and tolerability, your provider may increase your dose to the next level. Titration schedules follow ADA/AACE-aligned protocols.

Ongoing

Biomarker tracking begins (Care + Complete)

Weight, HbA1c trends, blood pressure, and other relevant markers are logged in your portal and reviewed at each check-in.

Phase 4 — Day 90

90-day comprehensive assessment.

At 90 days, your provider conducts a full progress review. This is where initial outcomes are most measurable and where long-term care planning happens.

Day 90

Comprehensive progress assessment

Full review of biomarkers, weight trajectory, medication tolerability, and goals alignment. Your provider updates your care plan for the next phase — which may include continued current therapy, dose adjustment, or transition to maintenance.

Typical 90-day outcomes (individual results vary)

5–10%

Average weight reduction at 12 weeks in clinical studies

0.5–1.5%

HbA1c reduction in patients with Type 2 diabetes

~80%

Members who continue past 90 days in current cohort

These figures are from published clinical literature and internal cohort data. Individual outcomes vary based on starting weight, medication, adherence, and other factors. Results are not guaranteed.

Ready to start your journey?

Assessment takes 3 minutes. No card required until your provider confirms eligibility.

Check my eligibility

Not medical advice. Outcomes vary. Results are not guaranteed.

Important Safety Information (ISI) — GLP-1 Receptor Agonists

GLP-1 receptor agonists (semaglutide, tirzepatide, liraglutide) are FDA-approved prescription medications. They are not appropriate for everyone. Do not use if you or a family member have a history of medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2).

Serious risks include: pancreatitis, gallbladder problems, kidney problems, hypoglycemia (in patients using insulin or insulin secretagogues), heart rate increase, suicidal ideation and behavior, and serious allergic reactions. Tell your provider about all medications you take and all medical conditions.

The most common side effects are nausea, diarrhea, vomiting, constipation, and stomach pain. These are usually mild and decrease over time.

Not for use in patients with type 1 diabetes. If you experience severe abdominal pain, stop the medication and seek immediate medical attention. For full prescribing information, consult your Meridian Health provider.